Efficacy, Safety and Underlying Mechanisms of Sphenopalatine Ganglion Acupuncture for Perennial Allergic Rhinitis

Exclusion Criteria

• •1\. oral steroids within 4 weeks prior to recruitment
• •2\. nasal steroids and/or antihistamine 2 weeks prior to recruitment
• •3\. seasonal AR
• •4\. any respiratory infection within the previous 4 weeks prior to recruitment
• •5\. history of nasal polyps, nasal septum deviation, asthma or autoimmune disorders
• •6\. previously received acupuncture therapy for AR within 1 month prior to recruitment
• •7\. women during pregnancy or lactation