Participants with a history of acute asthma exacerbation, respiratory tract infection or hospitalization for asthma in the last 4 weeks;
Known HIV-positive status or active hepatitis B or C virus test result
Participants with current evidence or history of uncontrolled coronary artery disease, congestive heart failure, myocardial infarction or cardiac arrhythmia;
Participants with current medical history of cancer and/or cancer treatment in the last 5 years;
Participants using medications that would have an effect on bronchospasm and / or lung function.
