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Change in Airway Peripheral Tone in COPD | Clinical Trials | Clareo Health

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UNKNOWNNCT04166812

Change in Airway Peripheral Tone in COPD

Small airways disease is a pathological feature in mild to moderate COPD, which might be causally involved in disease progression. However, there are only limited studies available that prospectively ...

Lead sponsor: Heidelberg University•2 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Heidelberg University

Collaborators

PD Dr. Henrik Watz, Pulmonary Research Center, LungenClinic Großhansdorf (Principal Investigator)
Chiesi GmbH, Hamburg, Germany (Funding)

Age

35 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•patients at risk for COPD
•smoking history (at least 10 pack years)
•absence of airway obstruction (FEV1/FVC ≥ 70% after salbutamol 400µg)
•high symptom score (CAT ≥ 10) or long acting bronchodilator therapy
•age \> 35 years
•smoking history (at least 10 pack years)
•mild COPD (FEV1/FVC \< 70% and FEV1 ≥ 70% after salbutamol 400µg)
•age \> 35 years

Exclusion Criteria

•respiratory infection within 4 weeks prior to inclusion
•other symptomatic pulmonary disease, except bronchial asthma
•patients with early COPD
•respiratory infection within 4 weeks prior to inclusion
•other pulmonary disease, except bronchial asthma

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: July 14, 2021Terms

Trial snapshot

StatusUNKNOWN

Phase—

Enrollment150

Start dateNov 2019

Last updatedJul 14, 2021

Condition

COPD COPD, Early-Onset

Locations shown

Pulmonary Research Institute at LungClinic Großhansdorf

Großhansdorf

Thoraxklinik at Heidelberg University

Heidelberg

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 14, 2021Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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