Age

18–any

Sex

ALL

Healthy volunteers

Not accepted

Patients with 18 years of age and older;
Ability to provide free and informed consent before entering the study;
Imaging diagnosis of a solid pancreatic lesion that was proposed for EUS characterization;
Presence of sectional imaging method (CT/MRI) performed within six months before randomization;
Blood test (blood count and coagulation studies) compatible with the performance of invasive maneuvers;
Clinical indication by the endoscopist for EUS-tissue acquisition with the use of an FNB needle.

Failure to provide free and informed consent;
Clinically significant change in haemostasis laboratory parameters: International Normalized Ratio (INR) \> 1.5; activated partial thromboplastin time (aPTT)\> 50 seconds; Platelets \<50,000;
Absence of a proper anticoagulant and/or anti-aggregate therapy discontinuation for the performance of FNB;
Absence of fasting (2h without clear liquids and 6h without solid foods);
Clinical suspicion of upper digestive tract obstruction;
An episode of acute pancreatitis within four weeks before echoendoscopy;
Respiratory failure or hemodynamic instability;
Pregnancy or breast-feeding.

Impact of Suction in the EUS-guided Fine Needle Biopsy of Solid Pancreatic Lesions