PRIMARY OBJECTIVES:
I. To evaluate the efficacy of transcranial direct current stimulation (tDCS) in reducing chemotherapy induced painful peripheral neuropathy (CIPPN).
Ia. Evaluate the change in pain scores Ib. Assess for changes in other symptoms (i.e insomnia, feeling of well-being, depression and anxiety).
SECONDARY OBJECTIVES:
I. To evaluate the following with the treatment of tDCS:
Ia. Assess for changes in using pain medications. Ib. Assess for changes in functioning (daily activities). Ic. Assess for changes in quality of life. Id. Assess for changes in neuropathy. Ie. Assess overall satisfaction with the tDCS treatment.
TERTIARY OBJECTIVES:
I. To evaluate tDCS treatment related side-effects.
OUTLINE:
Patients undergo tDCS once daily (QD) over 20 minutes 5 days each week (Monday-Friday) for 3 weeks.
After completion of study treatment, patients are followed up weekly for 3 weeks and at 4-6 weeks.