Using Smartphone Sensor Technology to Characterize Ambulatory Patterns of Participants With Peripheral Artery Disease

Exclusion Criteria

• •Lower extremity amputation(s) which interfere(s) with walking on the treadmill.
• •Individuals with critical limb ischemia defined by ischemic rest pain or ischemic ulcers/gangrene on the lower extremities
• •PAD of non-atherosclerotic nature (e.g., fibromuscular dysplasia, irradiation, endofibrosis)
• •Females who are pregnant
• •Coronary artery bypass grafts or major surgical procedures within 6 months prior to screening
• •Individuals whose walking exercise is primarily limited by symptoms of chronic obstructive pulmonary disease, angina, or heart failure
• •Individuals who have had a myocardial infarction within 3 months prior to screening
• •Individuals who have had a transient ischemic attack or stroke 3 months prior to screening
• •Individuals with uncontrolled hypertension (≥180 systolic or ≥100 diastolic resting blood pressure) during screening
• •Poorly controlled diabetes defined as glycated hemoglobin \>12%
• •Abnormal results of blood work not conducive to safely participating in an exercise trial (e.g., anemic, electrolyte abnormalities)
• •Inability to speak English
• •Other clinically significant cardiovascular, pulmonary, renal, endocrine, hepatic, neurological, psychiatric, immunological, gastrointestinal, hematological, or metabolic disease that is, in the opinion of the study team, not stabilized or may otherwise confound the results of the study