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COMPLETEDNANCT04109417

Effect of Platelet-Rich Plasma Biomembrane on Enhancing Bone Regeneration Following Endodontic Surgery

This study was conducted to evaluate clinical and radiographical outcome of using a standardized platelet-rich plasma (PRP) biomembrane following endodontic surgery and its correlation with the growth...

Lead sponsor: Alexandria University•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Alexandria University

15 healthy patients of both genders, between 20 and 45 years of age, presenting with 22 anterior/premolar teeth in need of endodontic surgery were recruited. Teeth presented with failed non-surgical root canal therapy and periapical radiolucency of ≥ 1cm in size. Patients were randomly divided following surgery into two groups, with 11 teeth each.

Age

20 - 45 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•1. Healthy patients.
•2. Selected tooth with previous root canal therapy failure and in need of endodontic surgery.
•3. Existence of a periapical radiographic lesion surrounding the root canal treated tooth, of size ≥ 1 cm.
•4. Healthy periodontal condition (probing depth, mobility \& epithelial attachment level are all within normal range).

Exclusion Criteria

•1. Leaking coronal restoration.
•2. Periodontal ligament breakdown and presence of apicomarginal defects.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: September 30, 2019Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment15

Start dateNov 2014

Last updatedSep 30, 2019

Condition

Endodontic Disease

Locations shown

faculty of dentistry, Alexandria University

Alexandria

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 30, 2019Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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