The Effects of Non-invasive Brain Stimulation on Treatment Adherence in Schizophrenia

Exclusion Criteria

• •1. Unwilling or incapable to consent to the study based on the MacArthur Test of Competence
• •2. Unstable medical or any concomitant major medical or neurological illness, including a history of seizures
• •3. Acute suicidal or homicidal ideation
• •4. Formal thought disorder rating ≥3 on the Positive and Negative Syndrome Scale (PANSS) P2 conceptual disorganization item
• •5. DSM-V substance dependence (except caffeine and nicotine) within 1 month of entering the study\*
• •6. Positive urine drug screen except for cannabis/marijuana at the screening visit
• •7. Metal implants or pacemaker precluding an MRI scan or other contraindications to MRI (eg., claustrophobia)
• •8. Pregnancy
• •9. Score \< 32 on the Wide Range Achievement Test-III
• •* Substance misuse: In addition to impaired insight, substance misuse is one of the principle contributors to medication nonadherence. To minimize the possibility of its influence, participants with a DSM-V diagnosis of substance dependence within 1 month of entering the study or a positive urine drug test (except for cannabis/marijuana) at the screening visit will be excluded. Substance use and urine drug screens will be assessed at subsequent study visits.