A Clinical Study to Assess the Effects of Various Dentifrice Technologies on Dentinal Hypersensitivity

Exclusion Criteria

• •having taken anti-inflammatory, analgesic, or psychotropic drugs, chronically;
• •chronic medical debilitating disease associated with constant or intermittent episodes of daily pain;
• •any home-care bleaching, whitening products or have had a professional bleaching treatment within 4 weeks of the Baseline visit;
• •dental prophylaxis within 2 weeks prior to Baseline visit;
• •having received professional desensitizing treatment or having used over-the-counter desensitizing products within 6 weeks of the Baseline visit;
• •having periodontal surgery, orthodontic treatment, or teeth restored in the preceding three months;
• •having teeth or periodontium with pathology or defects likely to cause pain;
• •having a history of allergies or hypersensitivity to ingredients in commercial dental products or cosmetics;
• •self-reported pregnancy or lactation;
• •having self-reported eating disorders, uncontrolled gastroesophageal reflux disease (GERD or Acid Reflux), excessive dietary or environmental exposure to acids, or other systemic conditions that are predisposing to dentinal hypersensitivity;
• •history or presence of kidney disorders, kidney stones, have celiac disease, inflammatory bowel disease (ulcerative colitis or Crohn's disease), chronic pancreatitis, have had intestinal or weight-loss surgery, or if have stomach or intestinal problems that keep them from absorbing certain foods or nutrients;
• •any diseases or condition that might interfere with the safe participation in the study;
• •inability to undergo study procedures;
• •having severe xerostomia;
• •having had active caries within the 12 months;
• •having high risk for caries development (rampant caries, multiple dental restorations, crowns with compromised margin) per examiners discretion;
• •teeth will be excluded from study measurements if they:
• •* have deep, defective, or facial restorations;
• •* have full crowns, extensive caries, cracked enamel, or are abutment teeth for fixed or removable prosthesis;
• •* present with tendency for spontaneous bleeding;
• •* have been scaled/root planed or restored within the past 3 months.