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Kidney Fibrosis and MRI | Clinical Trials | Clareo Health

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COMPLETEDNANCT03964948

Kidney Fibrosis and MRI

The investigators plan a prospective cross-sectional study of pediatric and adult healthy volunteers and patients with chronic kidney disease that will correlate a variety of quantitative MRI biomarke...

Lead sponsor: Children's Hospital Medical Center, Cincinnati•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Children's Hospital Medical Center, Cincinnati

Age

10 - 25 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Subjects who meet all of the following criteria will be eligible for the study:
•1. ≥ 10 and ≤ 25 years of age and;
•2. Kidney transplant patients, who have had a recent kidney biopsy (within 1 year) that shows interstitial fibrosis OR
•3. Patients with CKD Stage 2-5 who have previously had a biopsy (within 1 year) OR
•4. Lupus patients with active nephritis who will undergo biopsy evaluation before and after induction therapy OR
•5. Healthy Controls

Exclusion Criteria

•Subjects who meet any of the following criteria will be excluded from the study:
•1. Known contraindication to MR imaging (e.g., implanted non-MRI compatible device)
•2. Known or suspected pregnancy. Female subjects of child bearing potential will undergo a urine pregnancy test prior to imaging.
•3. Inability to undergo MRI without sedation/anesthesia.
•4. Non-English Speaking

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: September 9, 2021Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment37

Start dateAug 2018

Last updatedSep 9, 2021

Condition

Kidney Diseases

Locations shown

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 9, 2021Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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