About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

NGS for Non-unions | Clinical Trials | Clareo Health

Back to clinical trial search

UNKNOWNNCT03937310

NGS for Non-unions

The purpose of this study is to investigate the role of genetic testing to look for possible infection as a cause for failure of non-healing fractures. The study aims to compare the results of genetic...

Lead sponsor: Rothman Institute Orthopaedics•1 U.S. locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

Rothman Institute Orthopaedics

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Investigational group:
•Inclusion:
•2. Nonunions will be defined as a failure to progress towards expected union within an anticipated timeframe, and this judgment will be made by the attending caring for each patient. No specific timeframe or arbitrary cut points will be defined to allow for the considerable variation in fracture healing and different anatomical sites.
•3. Presumed Septic and Aseptic nonunions
•4. \>18 years old and able to provide informed consent

Exclusion Criteria

•Exclusion:
•1. Pathological fractures at index injury
•2. Patients on antibiotic therapy \<2 weeks prior to surgery
•Inclusion:
•1. Patients undergoing surgical intervention for nonunion following a traumatic closed long bone fractures (femur shaft, tibia, humerus)
•2. \>18 years old and able to provide informed consent
•Exclusion:
•1. Pathological fractures at index injury
•2. Patients on antibiotic therapy \<2 weeks prior to surgery

Related studies

RECRUITINGPhase 3

PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

NCT05699174 · Infections, Infected Wound, and more

Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care

NCT04299022 · Fractures, Bone, Nonunion of Fracture, and more

Distal Targeter vs Free-hand

NCT05613257 · Femur Fracture, Tibial Fractures, and more

Is Far Cortical Locking More Effective Than Bicortical Locking in Treating AO 43A1-3 Fractures?

NCT06005090 · Tibia Distal Fracture, Nonunion of Fracture of Tibia

Risk Factors for Post-Operative Nonunion of Tibial Shaft Fractures Based on a Path Analysis Model

NCT03928912 · Nonunion of Fracture of Tibia (Diagnosis)

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 3, 2019Terms

Trial snapshot

StatusUNKNOWN

Phase—

Enrollment120

Start dateJan 2019

Last updatedMay 3, 2019

Condition

Nonunion of Fracture

Locations shown

Rothman Institute

Philadelphia, Pennsylvania

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 3, 2019Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions