Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Alnylam Pharmaceuticals
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Has mild to moderate hypertension with mean sitting systolic blood pressure (SBP) of \>130 and ≤165 mmHg without hypertensive medication for Parts A, B and D, and \>135 and ≤165 mmHg without hypertensive medication for Part E
Parts A and B: Has body mass index (BMI) ≥18 and ≤35 kg/m\^2; Part D: Has BMI \>35 and ≤50 kg/m\^2; Part E: Has BMI ≥18 kg/m\^2 and ≤50 kg/m\^2
Has a normal 12-lead electrocardiogram (ECG)
Is a nonsmoker
You may not be if
Has secondary hypertension
Has orthostatic hypotension
Has estimated glomerular filtration rate (eGFR) of \<60 mL/min/1.73m\^2
Recently received an investigational agent
Has diabetes mellitus
Has history of any cardiovascular event
Has history of intolerance to SC injection(s)
Clareo Health | A Study to Evaluate ALN-AGT01 in Patients With Hypertension
