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COMPLETEDNCT03927118

Effect of Dexamethasone Implant on Optic Disc

This study evaluates the effect of dexamethasone implant which is an intraocular corticosteroid on the optic nerve fibers. Retinal nerve fiber thicknesses and optic nerve head pitting rates were measu...

Lead sponsor: Bulent Ecevit University•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Bulent Ecevit University

Diabetic macular edema is the most frequent ocular complication of diabetes resulting in irreversible loss of vision if untreated. Dexamethasone implant implant is used to treat macular edema due to diabetes. It stay in the vitreous for 6 months after intravitreal administration. Dexamethasone implant can lead to retinal nerve fiber layer and optic nerve damage by both increasing intraocular pressure and its direct effect on neural tissue during the effective 6-month period.

Age

20 - 80 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Patients who underwent first time intravitreal injection

Exclusion Criteria

•Previously received any surgery
•Proliferative diabetic retinopathy
•Glaucoma or glaucoma suspicion
•Optic disc fatigue
•Optic disc edema
•Uveitis and media opacity
•Blurred of image clarity

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 13, 2019Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment43

Start dateFeb 2018

Last updatedMay 13, 2019

Condition

Glaucoma and Ocular Hypertension Diabetic Macular Edema Intravenous Drug Usage Optic Disk Disorders

Locations shown

Zonguldak Bülent Ecevit Üniversitesi.

Zonguldak, Kozlu

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 13, 2019Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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