Tele-Coaching Intervention to Improve Treatment Adherence in Cystic Fibrosis

Inclusion Criteria

• •COACH Participants:
• •1\. Be a CF-focused clinician employed by one of the study sites, including: social workers; respiratory therapists, pharmacists, nurse practitioners, nurses, mental health coordinators, dieticians, and psychologists.
• •PATIENT Participants:
• •1. Male or female ≥ 14 and ≤ 25 years of age;
• •2. Documentation of a CF diagnosis as evidenced by one or more clinical features consistent with the CF phenotype and one or more of the following criteria: (a) sweat chloride \> 60 mEq/L by quantitative pilocarpine iontophoresis test (QPIT), and/or (b) two well-characterized mutations in the CFTR (cystic fibrosis transmembrane conductance regulator) gene;
• •3. Has been prescribed one or more respiratory nebulized medications, such as: (a) dornase alfa, (b) hypertonic saline, (c) inhaled tobramycin, (d) inhaled aztreonam, (e) inhaled colistimethate \*and/or\* uses a vest device for airway clearance;
• •4. If taking, or anticipating to start on, Trikafta, has been taking the modulator for 6 weeks prior to enrolling in the study;
• •5. Has access to necessary resources for participating in a technology-based intervention: (a) mobile phone, tablet, computer, or digital camera capable of capturing and sending a digital image, and access to Internet; (b) an email account;
• •6. Is English-speaking;
• •7. Endorsed score of ≥3 on any treatment component on the CF-CBS at Enrollment Visit.
• •CAREGIVER Participants:
• •1. Is a caregiver of and resides with a Patient Participant in this study;
• •2. Has received permission from the Patient Participant, if aged 18 years of age or older, to be in the study; and
• •3. Is English-speaking.