12-Month Once-a-week HIIT Improves Body Adiposity and Liver Fat

Exclusion Criteria

• •1. ≥150 minutes moderate-intensity exercise or ≥75 minutes vigorous exercise weekly,
• •2. Regular HIIT (≥1 weekly) in the past six months,
• •3. Medical history of cardiovascular disease, chronic pulmonary or kidney disease, heart failure, cancer, and liver disease except for NAFLD,
• •4. Somatic conditions that limit exercise participation (e.g., limb loss),
• •5. Impaired mobility due to chronic diseases (e.g., chronic arthritis/osteoarthritis, neurological, musculoskeletal and autoimmune diseases),
• •6. Daily smoking habit,
• •7. Excess alcohol consumption (daily ≥30 g of alcohol for men and ≥20 g for women) in the past six months
• •8. Surgery, therapy or medication for obesity or weight loss in the past 6 months (e.g., gastric bypass, gastric band, sleeve gastrectomy, gastric reduction duodenal switch, and dietitian-prescribed dietary program).
• •9. During the study period, subjects identified with major physical changes that would considerably affect their body composition and weight (e.g., anorexia nervosa, bulimia nervosa, and prolonged gastrointestinal and digestive disorders) will be excluded.