THREE-row Circular STAPLER in Low Anterior Resection for Rectal Cancer

Inclusion Criteria

• •1. Provision of signed and dated informed consent form
• •2. Stated consent to comply with all study procedures and availability for the duration of the study
• •3. Male or female
• •4. For females of reproductive potential: not pregnant at the time of screening
• •5. For males of reproductive potential: use of condoms or other methods to ensure effective contraception with partner
• •6. Histologically proven primary rectal adenocarcinoma located within 5 to 15 cm from anal verge not involving internal and/or external sphincter muscle
• •1. Current use of antiplatelet drugs, acetylsalicylic acid or anticoagulants within 7 days prior to intervention
• •2. Unresectable tumour, inability to perform a TME with colorectal anastomosis, inability to complete R0 resection or presence of T4b tumour necessitating a multi-organ resection
• •3. Inability to save the left colic artery
• •4. Diameter of rectal lumen is unable to contain the working part of the stapler
• •5. Infection requiring antibiotic treatment within 30 days prior to intervention
• •6. Anal incontinence prior to surgery (Wexner Continence Grading Scale \>=10)
• •7. Significant comorbidities - ASA \> III