Safety and Efficacy Study of Human T Lymphoid Progenitor (HTLP) Injection After Partially HLA Compatible Allogeneic Hematopoietic Stem Cell Transplantation in SCID Patients

Inclusion Criteria

• •Pediatric patients affected by any type of SCID confirmed by clinical, immunological and/or molecular diagnosis and eligible for an allogeneic HSCT
• •Absence of a matched sibling donor or a matched unrelated donor (MUD) 10/10
• •Clinical conditions incompatible with the search of a MUD
• •Written, informed consent of parents/ legal representative (child)
• •Age ≤ 2 years at the time of screening
• •No prior therapy with allogeneic stem cell transplantation
• •No treatment with another investigational drug within one month before inclusion
• •Patient affiliated to social security