Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Ohio State University
With
National Center for Complementary and Integrative Health (NCCIH)
University of Michigan
This research will see how brain activity and brain connectivity is affected by Mindfulness Based Cognitive Therapy (MBCT) and an active comparison therapy called Muscle Relaxation Therapy (MRT). Participants that qualify to be in this study will be randomly assigned to receive 8 weeks of group therapy in either MBCT or MRT treatments. Prior to receiving therapy participants will: complete baseline assessments related to their PTSD; fill out surveys; have an functional magnetic resonance imaging (fMRI); and provide saliva samples. These assessments will be repeated after the therapy is over. Overall study participation should last approximately 10-12 weeks.
Due to COVID precautions, treatments shifted from in-person to remotely-delivered ("Zoom" video-conferencing) modality.
Age
18–72
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Meets current Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) criteria for PTSD (with or without Major Depressive Disorder) or subsyndromal PTSD (has qualifying trauma, has intrusive and avoidant symptoms, and at least one negativity and one arousal symptom, and significant impairment); type of trauma shall be interpersonal violence, combat, and/or sexual assault, etc.
You may not be if
Dissociative PTSD
Delayed-onset PTSD
Magnetic Resonance Imaging (MRI) contraindications (e.g. metal in body, inability to be in the scanner - claustrophobia, severe back pain, etc.)
Serious medical or neurologic conditions (e.g. stroke, seizures)
Suicide risk
Psychosis
Life history of schizophrenia
Life history of bipolar disorder
Current substance dependence
Other factors that preclude safe and meaningful participation in the study, at discretion of the PI and study team
Clareo Health | Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD)
