Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy Subjects

Inclusion Criteria

• •Patients with primary open angle glaucoma
• •Diagnosis of manifest primary open angle glaucoma defined as pathological optic disc appearance
• •Glaucoma hemifield test outside normal limits
• •Untreated IOP ≥ 21 mmHg on at least three measurements in the medical history
• •Mean deviation in the visual field test is less than or equal 10dB (for one group) OR more than 10dB (for the other group)
• •Patients with normal tension glaucoma
• •Diagnosis of manifest normal tension glaucoma defined as pathological optic disc appearance
• •Glaucoma hemifield test outside normal limits
• •No evidence of untreated IOP \> 20 mmHg in the medical history
• •Mean deviation in the visual field is less than or equal 10dB (for one group) OR more than 10dB (for the other group)
• •Patients with ocular hypertension
• •Normal ophthalmic findings except presence of ocular hypertension defined as untreated IOP ≥ 21 mmHg on at least three measurements in the medical history
• •No signs of glaucomatous damage in the optic disc
• •or the glaucoma hemifield test
• •Healthy control subjects
• •Normal ophthalmic findings
• •IOP \< 20 mmHg on least three measurements
• •No evidence of increased IOP in the medical history
• •No signs of glaucomatous damage in the optic disc
• •or the glaucoma hemifield test