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Keep this study
Lead
University of Illinois Chicago
Female volunteers will be recruited from the community for participation in this 3-menstrual cycle study. In the first two menstrual cycles, study participants will chart their symptoms and and ovulation. Study participants will continue to perform ovulation testing during their third menstrual cycle in which they will attend one individualized task session and provide 8 serum samples at different timepoints across the menstrual cycle. Primary analyses will contrast neuroactive hormone trajectories across the menstrual cycle and stress reactivity according to study groups (PMDD vs healthy).
Age
18–35
Sex
FEMALE
Healthy volunteers
Accepted
You may be eligible if
Female
Aged 18-35 years, established by visual inspection of a government-issued ID
Average menstrual cycle 21-35 days
You may not be if
Lifetime DSM-5 Axis 1 disorder (except anxiety and depression), as documented in the Mental Health Interview
Current DSM-5 Axis depressive or anxiety disorder, as documented in the Mental Health Interview
Positive urine drug screen test
Breath alcohol concentration \>0.00%
Self-reported smoker or carbon monoxide concentration ≥ 6 ppm
Irregular menstrual cycle
Current pregnancy (urine test-verified) or lactation, or a plan to become pregnant
Moderate or high suicide risk
Shipley IQ (vocabulary standard score) \> 80
Any prescription medications (including hormonal forms of birth control)
Clareo Health | Premenstrual Hormonal and Affective State Evaluation (PHASE) Project