Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
The University of Texas Health Science Center, Houston
Age
21–40
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
treatment-seeking individuals diagnosed with AUD diagnostic statistical manual 5 (DSM-5)
fluent in English
past month excessive alcohol use (\>7 drinks/week for woman, \>14 drinks/week for men, \>3 drinks/occasion for women\>4 drinks/occasion for men)14
baseline Hamilton Anxiety Rating Scale (HAM-A) or Perceived Stress Scale (PSS) core indicative of mild to moderate anxiety (score 8 to 23) or moderate stress (score 14 to 26), respectively
increase in alcohol craving following the baseline stress reactivity assessment.
You may not be if
Individuals will be excluded for exhibiting severe scores on the HAM-A, PSS, or post-traumatic (PTSD) checklist (PCL-5) at the discretion of the admitting physician
physical dependence on alcohol Alcohol Use Disorders Inventory (AUDIT) score indicative of severe alcohol dependence (≥13 for women, ≥15 for men)
greater than mild substance use disorder on drugs other than alcohol, nicotine, and marijuana
contraindications for taking pioglitazone; medical conditions contraindicating pioglitazone pharmacotherapy or taking contraindicated medications
be pregnant, nursing, or planning on becoming pregnant during the course of the study
have any other illness, condition, or use of medications, which in the opinion of the PI and/or admitting physician would preclude safe and/or successful completion of the study.
Clareo Health | Effects of Pioglitazone on Stress Reactivity and Alcohol Craving (Pilot)
