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Active Not RecruitingNANCT03860168

PICU Up!: A Pilot Stepped-wedge Trial of a Multicomponent Early Mobility Intervention for Critically Ill Children

Recent decreases in Pediatric Intensive Care Unit (PICU) mortality rates have been offset by increased morbidity and length of stay for vulnerable young patients. Heavy sedation, bedrest, and delirium...

Lead sponsor: Johns Hopkins University•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Johns Hopkins University

Collaborators

Donaghue Medical Research Foundation

Age

0 - 24 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Participating PICUs must be a separate physical space dedicated to the care of critically ill infants and children, with the ability to provide mechanical ventilation.
•Not implemented a PICU mobility protocol and would commit to not implementing a mobility protocol until the randomized time of unit implementation.
•Admitted to the participating PICU ≥ 3 days.

Exclusion Criteria

•Patients with an active do-not-resuscitate (DNR) order will be excluded.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: December 22, 2025Terms

Trial snapshot

StatusACTIVE_NOT_RECRUITING

PhaseNA

Enrollment2,500

Start dateApr 2019

Last updatedDec 22, 2025

Condition

Critical Illness

Locations shown

Johns Hopkins Hospital

Baltimore, Maryland

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 22, 2025Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions