Immuno-regulatory Profiling of T Cells in GVHD Treated With Extracorporeal Photopheresis

Exclusion Criteria

• •1. Patients who are unable to tolerate the volume shifts associated with ECP treatment due to the presence of any of the following conditions: uncompensated congestive heart failure, pulmonary edema, severe asthma or chronic obstructive pulmonary disease, hepatorenal syndrome.
• •2. Active bleeding.
• •3. International normalized ration (INR) \>2.
• •4. Patients with known hypersensitivity or allergy to psoralen.
• •5. Patients with known hypersensitivity or allergy to both citrate and heparin.
• •6. Patients with co-existing photosensitive disease (e.g. porphyria, systemic lupus erythematosus, albinism) or coagulation disorders.
• •7. Active, uncontrolled infection