Blood and Stool Sample Collection in Subjects Participating in Colorectal Cancer Screening: Act Bold

Exclusion Criteria

• •Any previous cancer diagnosis (with the exceptions of basal cell or squamous cell skin cancers) and/or cancer related treatment (e.g. chemotherapy, immunotherapy, radiation, and/or surgery) within the past 5 years.
• •Subject has a diagnosis or personal history of any of the following conditions, including:
• •1. Familial adenomatous polyposis (also referred to as "FAP", including attenuated FAP and Gardner's syndrome).
• •2. Hereditary non-polyposis CRC syndrome (also referred to as "HNPCC" or "Lynch Syndrome").
• •3. Other hereditary cancer syndromes including but are not limited to Peutz-Jeghers Syndrome, MYH-Associated Polyposis (MAP), Turcot's (or Crail's) Syndrome, Cowden's Syndrome, Juvenile Polyposis, Neurofibromatosis and Familial Hyperplastic Polyposis.
• •Subject has a family history of:
• •1. Familial adenomatous polyposis (also referred to as "FAP").
• •2. Hereditary non-polyposis CRC syndrome (also referred to as "HNPCC" or "Lynch Syndrome").
• •Subjects with Cronkhite-Canada Syndrome.
• •IV contrast (e.g. CT and MRI) within 1 day \[or 24 hours\] of blood collection.
• •Subject has any condition that in the opinion of the Investigator should preclude participation in the study