Efficacy Management and Adherence Evaluation of Diclofenac in the Treatment of Knee Osteoarthritis Pain

Inclusion Criteria

• •According to the OA diagnostic criteria of knee joint, the side with higher WOMAC score is defined as observing knee joint for patients with both knees conforming to OA diagnostic criteria.
• •1. Repeated knee pain in the past month
• •2. X-ray showed narrowing of articular space, subchondral sclerosis and/or cystic degeneration, and formation of osteophyte at articular margin.
• •3. Joint fluid (\> 2 times) is cool and sticky, WBC \< 2000/ml
• •4. Age over 40
• •5. Morning stiffness less than 30 minutes
• •6. Bone fricative (sensation) during exercise According to 1+2 or 1+3+5+6 or 1+4+5+6, OA of knee joint can be diagnosed.
• •7. The informed consent has been signed