Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
New York Medical College
With
Johns Hopkins University
Age
2–40
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
SCD-associated ACS with the presence of any two or more of the following signs not explained by other etiologies: Fever, Chest pain, Cough, Dyspnea, Tachypnea for age, Pulmonary infiltrate on CXR and/or Chest CT scan, Decreased O2 saturation with or without oxygen supplement;
Age 2 to 40 years of age;
Homozygous Hemoglobin S Disease, Hemoglobin SC Disease or Hemoglobin S 0/+ thalassemia;
Informed consent/assent;
Consent of patient/parent within ≤72 hours after inpatient admission for SCD-associated ACS.
Females of childbearing age will have a negative pregnancy test.
You may not be if
Current Grade III or IV hemorrhage;
Previous hypersensitivity reaction to defibrotide;
Current systemic anti-coagulant therapy and/or fibrinolytic therapy;
Consent of patient/parent greater than 72 hours of inpatient admission for SCD-associated ACS;
No signed informed consent
Clareo Health | Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome
