Institut National de la Santé Et de la Recherche Médicale, France
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
COHORT 1
Histologically confirmed cutaneous or mucosal melanoma (per American joint committee on cancer (AJCC) staging system) that is unresectable or metastatic
No prior systemic anticancer therapy for unresectable/metastatic melanoma or clinical/radiological disease progression (RECIST1.1) if previously treated and before new treatment
No prior malignancy active within the previous 3 years except for locally curable cancers that have been apparently cured, such as cutaneous carcinoma or cervix)
followed in Saint Louis Hospital
Tumor tissue available in Saint Louis Hospital
Subjects must have signed and approved written informed consent form
No pregnancy
Any positive test for hepatitis A virus, hepatitis B virus or hepatitis C virus indicating acute or chronic infection, and/or detectable virus
Histologically confirmed cutaneous or mucosal melanoma
Candidates for sentinel lymph node analysis and surgical recovery (this examination is in practice reserved for melanomas \>1mm thick or ulcerated)
No prior adjuvant anticancer therapy
followed in Saint Louis Hospital
Tumor tissue available in Saint Louis Hospital
Subjects must have signed and approved written informed consent form
No pregnancy
Any positive test for hepatitis A virus, hepatitis B virus or hepatitis C virus indicating acute or chronic infection, and/or detectable virus
You may not be if
None
COHORT 2 :
None
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