Finding studies
Finding studies
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Lead
Michael J. Fox Foundation for Parkinson's Research
With
Specific aims to accomplish this objective are: PRIMARY OBJECTIVES: * To evaluate a series of extracellular vesicle isolation methods for their ability to enrich for LRRK2 and increase the detection of LRRK2 in CSF samples. * To compare the measurements of LRRK2, p1292 LRRK2, Rabs and pRabs from the ECVs isolated using each method. * To assess the inter-lab reliability of each method SECONDARY OBJECTIVES * To assess the ability of the network of sites to efficiently conduct a study involving biosample collection for PD research. Efficiency will be assessed using measures of the time taken to meet specific milestones within the study * To assess the ability of the network to collect high quality biospecimens adhering to agreed-upon protocols. * To gauge the willingness of participants to participate in subsequent Fox BioNet studies
Age
18–any
Sex
ALL
Healthy volunteers
Accepted