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COMPLETEDPhase 4NCT03716076

Carbetocin on Myocardial Repolarization Dynamics in Obstetrics Study

Relationship between carbetocin dose on transmural dispersion of repolarization (TDR).

Lead sponsor: University of British Columbia•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

University of British Columbia

Carbetocin is a uterotonic used to prevent postpartum hemorrhage. Although it has been proven to be completely safe, little is known about its effects on the electrical activity of the heart. The investigators aim to determine its effect on myocardial repolarization dynamics

Age

19 - No limit years

Sex

FEMALE

Healthy Volunteers

Yes

Inclusion Criteria

•Pregnant patients ≥ 36 weeks gestation, for elective Cesarean delivery under neuraxial anesthesia
•American Society of Anesthesiologists (ASA) class 2
•Patients ≥ 19 years of age

Exclusion Criteria

•Long QT syndrome
•Cardiac disease or rhythm abnormalities
•Family history of long QT syndrome or abnormal cardiac conduction
•Currently taking medication that is known to prolong the QT interval
•Women who are high risk for uterine atony as outlined in SOGC
•Known allergic reaction or hypersensitivity to Carbetocin or any other oxytocin homologue
•Patients who are unable to give informed consent because of a language barrier as the study team only speaks English and will be unable to complete consent process and study procedure appropriately.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 14, 2021Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE4

Enrollment50

Start dateNov 2018

Last updatedMay 14, 2021

Condition

Cardiac Arrythmias

Locations shown

BC Women's Hospital

Vancouver, British Columbia

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 14, 2021Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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