Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Helsinki University Central Hospital
Please see study protocol
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patient not responding to conservative treatment of 3 months of nasal steroid drops
Nasal polyp score ≥ 4/8
SNOT-22 ≥ 30
Lund-Mackay CT score ≥ 14
One previous endoscopic sinus surgery or at least one peroral corticosteroid course or at least 3 courses of antibiotics within 2 years
You may not be if
Age \<18 years, age \> 65 years
Complication of CRS (f.e. mucocele, invasive fungal rhinosinusitis)
Other diagnosis than CRSwNP (inverted papilloma, antrochoanal polyp etc.)
Previous external sinus surgery or Draf 3 procedure (or indication for external approaches or Draf 3
Bleeding diathesis
Pregnancy/ breastfeeding
Cystic fibrosis
Primary ciliary dyskinesia (PCD)
Sarcoidosis
Granulomatosis with polyangitis (GPA)
Eosinophilic granulomatosis with polyangitis (EGPA)
Immunosupression (diagnosed Spesific Antibody Deficiency (SAD), common variable immunodeficiency (CVI), HIV or use of biologicals/immunosuppressive medication)
Immunotherapy
Daily use of systemic corticosteroids
Communication problems (f.e. neurological/psychiatric disease, language skills)
