Serious cardiac pathology or musculoskeletal problems that would limit exercise ability

MNSI score \< 1

Current open wound or history of plantar ulcer for the last 3 months

Partial foot amputations

Inability to ambulate without assistive device

Stroke or other central nervous system pathology

Stage 2 hypertension (resting blood pressure \>160 systolic or \>100 diastolic)

Contraindications to 3T whole body MRI scanners (e.g., pacemaker, cerebral aneurysm clip, cochlear implant, presence of shrapnel in strategic locations, metal in the eye, claustrophobia, or other problems).

Subjects with alcoholism, chronic drug use, chronic gastrointestinal disease, or renal or hepatic impairment

Pregnant women and children

Reversing Diabetic Peripheral Neuropathy Through Exercise

What this study is about