Maintenance Treatment of Chidamide in Stage IV or Relapsed/Refractory Extranodal NK/T-cell Lymphoma

Inclusion Criteria

• •1. diagnosis of NKTCL with typical morphology and immunophenotype, according to the 2008 World Health Organization classification of lymphomas;
• •2. newly-diagnosed stage IV disease or relapsed or refractory disease；
• •3. age ≥ 18 years;
• •4. ECOG performance status 0-2;
• •5. at least one measurable lesion;
• •6. adequate hematological, hepatic, and renal functions; e.g., absolute neutrophil count ≥ 1.5 × 109/L, platelet count ≥ 80 × 109/L, total bilirubin ≤ 1.5 × upper limit of normal, alanine transaminase and aspartate transaminase ≤ 2 × upper limit of normal, and creatinine ≤ 1.5 mg/dl;
• •7. life expectancy of more than 3 months.