Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Hospital Universitario La Fe
PRIMARY OBJECTIVES:
To evaluate the association between Mu opioid receptor 1 (MOR-1) expression in patients with colorectal cancer stage II / III submitted to scheduled curative surgery and disease-free survival (DFS) five years follow up after surgery.
SECONDARY OBJECTIVES:
To evaluate the association between the MOR-1 expression in patients with colorectal cancer stage II / III undergoing scheduled curative surgery and overall survival (OS) five years follow up after surgery.
To evaluate the association between MOR-1 expression in patients with colorectal cancer stage II / III submitted to scheduled curative surgery and perioperative complications until postoperative day 28th after surgery.
To evaluate the association between perioperative opioids dose (morphine equivalents) and disease-free survival/overall survival until five years after surgery.
To evaluate MOR-1 expression differences in paraffin samples from patients with colorectal cancer stage II / III submitted scheduled colorectal surgery between the tumor tissue and the adjacent nontumorous tissue.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients older than 18 years.
Colorectal scheduled surgery between January 2010- December 2013.
Colon / rectum neoplasia Stage II / III (T3 / T4 N + M0).
