Investigating the Effects of Mikei® Red Reishi Essence EX on the Immune System of Prostate Cancer Patients and Patients With Non-cancerous Conditions of the Prostate

Exclusion Criteria

• •1. Patients taking mushroom (including reishi) or other herbal products/natural supplements
• •2. Patients with a known allergy to mushrooms
• •3. Prisoners
• •6. Patients taking warfarin, heparin, Aspirin \>81mg/day, or other prescribed blood thinners: Reishi may increase the risk of bleeding.
• •7. Patients with platelets levels below 139 X 103/ul or history of bleeding disorders
• •8. Patients undergoing chemotherapy: Reishi may make some chemotherapy drugs less effective.
• •9. Patients with any known immune disorder, including but not limited to HIV or other primary or secondary immune deficiency diseases, autoimmune diseases, history of or being considered for organ transplants, etc.
• •10. Patients taking immunosuppressants (Corticosteroids, Calcineurin inhibitors, mTOR inhibitors, IMDH inhibitors, Biologics, Monoclonal antibodies): Reishi can stimulate immune responses.
• •11. Patients taking cytochrome P450 2E1, 1A2, and 3A sensitive substrate drugs: Reishi may increase the risk of side effects of these drugs.
• •12. Patient has total bilirubin \>1.5 MG/DL, alanine aminotransferase (ALT) \>51 U/L or aspartate aminotransferase (AST) \>46 U/L.