The participants of the study will be divided in two groups: (1) a group with caloric restriction and without restriction in time for feeding and (2) a group with caloric restriction and restriction in time for feeding. This second group will be subdivided according to the participant's preference: (2.1) first meal at 8 a.m. and last meal at 4 p.m. or (2.2) first meal at 12 p.m. and last meal at 8 p.m. The caloric restriction for all participants will be 513 to 770 kcal from estimated energy requirement.
Age
18–59
Sex
FEMALE
Healthy volunteers
Accepted
You may be eligible if
Females;
Aged between 18 and 59 years old;
Body mass index equal or greater 25 kg/m²;
Agree to sign the informed consent.
You may not be if
Any chronic health conditions (e.g. chronic renal failure, autoimmune, heart, and liver disease);
Thyroid diseases or medications for its treatment;
Medications known to affect total energy expenditure;
Use of steroids, immunosuppressants or non-steroidal anti-inflammatory drugs, weight-loss medications, oral hypoglycemic agents or insulin and any medications that influence metabolic and/or inflammatory parameters;
