Evaluation of the Effect of a Shiitake Extract on Lipid Profile in Subjects With Moderate Hyperlipidemia

Exclusion Criteria

• •Individuals diagnosed with Diabetes Mellitus type 1.
• •Individuals diagnosed with Diabetes Mellitus type 2 on pharmacological treatment (unless it is possible the suspension 30 days before the trials).
• •Individuals with dyslipidemia on pharmacological treatment;
• •Individuals with hypertension on pharmacological treatment;
• •Individuals \> 60 years smokers with total cholesterol \> 200mg/dL or LDL \>130mg/dl.
• •Individuals with hypertension on pharmacological treatment uncontrolled.
• •Individuals with hyperthyroidism and hypothyroidism on pharmacological treatment uncontrolled.
• •Individuals allergic to Shiitake (Lentinula edodes)
• •Individuals with chronic diseases (hepatic, kidney, …)
• •Individuals receiving at least the preceding 2 months a pharmacological treatment that modifies the lipid profile (for example, statins, fibrates, diuretics, corticosteroids, ADOs);
• •Individuals who have participated in the last 6 months in a program or clinical trial to lose weight.
• •Smokers wanting to stop to smoke during the period that clinical trial lasts.
• •Individuals with mental illness.
• •Consume drugs to lose weight during 30 days before starting the study
• •Pregnant or breastfeeding women.