Synaptic Plasticity and Cognitive Function in RASopathies

Inclusion Criteria

• •1. Group 1: NS, Group 2: NF1 (both genetically assured)
• •2. Age ≥16 years
• •3. The adolescent (≥16) and legal guardian who are capable to give their consent and understand the aim and rationale of the study. In case of doubts, an independent medical practitioner will evaluate the capacity to consent.
• •4. Signed informed consent if ≥ 16 years and legal guardian.
• •5. Persons who are ≥ 18 years old and capable to give their consent and understand the aim and rationale of the study. In case of doubts, an independent medical practitioner will evaluate the capacity to consent.
• •6. Signed informed consent if ≥ 18 years.
• •7. Male participants and female participants who are not capable of bearing children or who use a method of contraception that is medically approved by the health authority of the respective country.