Contrast Enhanced Ultrasound in Human Crohn's Disease-Lumason

Exclusion Criteria

• •Patients under the age of 10 or over the age of 18.
• •Pregnancy or breast feeding. Urine pregnancy testing will be performed on all female study participants of reproductive potential.
• •Obesity/body habitus preventing visualization of small bowel affected by Crohn's disease by ultrasound (Body mass index ≥30 kg/m2
• •Subject inability/unwillingness to consent or child assent, including severe developmental delay/mental retardation.
• •Prior allergic-like reaction or other severe adverse event to Lumason or any of the active ingredients in Lumason (SPECIFIC CONTRAINDICATION from Package Insert).
• •Known unstable cardiopulmonary conditions (including any history of acute myocardial infarction/acute coronary artery syndrome, arrhythmia, and congestive heart failure), ongoing acute or chronic kidney disease (eGFR \<30 ml/min), moderate/severe chronic lung disease, and end-stage liver disease.