Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of California, Los Angeles
Age
21–45
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Age between 21 and 45
2. Meet DSM-5 criteria for current Moderate-to-Severe AUD
3. Current Heavy Drinking (\> 14 drinks per week for men; \> 7 drinks per week for women), as indicated by self-reported drinking for the 30 days prior to screening
4. Have reliable internet access
You may not be if
1. Currently receiving or seeking treatment for AUD\*
2. Past year DSM-5 diagnosis of any substance use disorder other than alcohol or nicotine
3. A lifetime diagnosis of schizophrenia, bipolar disorder, or any psychotic disorder
4. Current use of drugs, other than marijuana, verified by a urine toxicology screen\*
5. Pregnant, nursing, or refusal to use reliable birth control (if female)\*
6. A medical condition that may interfere with safe participation (e.g., unstable cardiac, renal, or liver disease, uncontrolled hypertension, diabetes, or AST, ALT, or GGT ≥ 3 times upper normal limit)
7. Self-reported recent (i.e. past 30 day) use of medications that are contraindicated with ibudilast\*
8. Non-removable ferromagnetic objects in body
9. Claustrophobia
10. Serious head injury or prolonged period of unconsciousness (\>30 minutes)
* Participants who meet these criteria at any point during the course of the study (i.e. after randomization) will be withdrawn from the study for safety purposes.
Clareo Health | Ibudilast and Withdrawal-Related Dysphoria
