Cognitive deficits in people with psychosis have been shown to have negative impact on functional goals including the ability to work and perform daily tasks. Cognitive Remediation Therapy (CRT) is a psychological therapy developed to improve cognitive functions in people with schizophrenia but ultimately with a focus on improving social and functional outcomes. There is evidence that CRT is effective in improving cognition and functioning but there is still a limited understanding of the mechanisms responsible for different treatment responses. This study attempts to fill this gap by developing and testing a new form of CRT, which will personalise therapy elements according to participants' characteristics. The therapy will consist of task practice using a computerised Cognitive Remediation software and supervised activities supported by a therapist to boost functioning. The knowledge gathered in this work will contribute to develop the next generation of personalised treatment approaches for people with schizophrenia.
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
a range of 18-65 years
English speaking or with a good knowledge of the language
a diagnosis of schizophrenia or schizoaffective disorder according to the DSM- V
at least one year contact with mental health services,
a deficit (of at least one standard deviation below the mean) in at least one cognitive domain out of these three cognitive domains: memory, executive function and information processing.
You may not be if
Planned medication change
Diagnosis of learning disability
Presence of cognitive deficits related to organic causes or head injury
Primary diagnosis of substance dependence
Clareo Health | Personalised Cognitive Remediation Therapy (pCRT)
