Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospital, Grenoble
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Severe eosinophilic asthma
Patient on inhaled therapy with inhaled corticosteroid and long-acting bronchodilator for at least 6 months
Patient under oral corticosteroid therapy (prednisolone or prednisone) for at least 6 months and unmodified in the last 4 weeks before the first injection
Patient able to provide informed and written consent
Obtaining the temporary authorization for nominative use for mepolizumab
You may not be if
Chronic pulmonary pathology other than asthma
Active neoplasia
Active liver disease
Serious and uncontrolled cardiovascular pathology (LVEF less than 30%, NYHA IV, ...)
Other eosinophilic pathology (Churg \& Strauss syndrome, parasitic infection, ...)
Hypersensitivity to mepolizumab or excipient
Immunity disorders
Patient not affiliated to a social security system
