FET-PET/MRI for Surgical Assessment of Pediatric Brain Tumors

Inclusion Criteria

• •1. Patient must have a known or suspected primary brain tumor with a non-enhancing component with planned standard of care surgical resection. Patients with newly diagnosed or recurrent brain tumors are eligible.
• •2. Tumors with non-enhancing regions will be defined as T2/FLAIR hyperintensity extending at least 0.5 cm beyond areas of enhancement as assessed by MRI.
• •3. Patient must be 18 years of age or younger at the time of study enrollment.
• •4. Patient must have measurable disease defined as tumor measurable in two perpendicular dimensions on MRI greater than 1 cm.
• •5. Patient must have a life expectancy greater than 8 weeks.
• •6. Patient must be able to undergo FET-PET/MRI without sedation.
• •7. Females with childbearing potential must have a negative urine β-hCG test on the day of procedure or a serum hCG test within 48 hours prior to the administration FET. Females who have not reached menarche will not require pregnancy testing.