* Injection of the isotopic tracer in standard form and in the usual preoperative period (hours-day).
* Identical injection in three-four punctures of 2 mL of Sienna+ ® and local massage of 5-10 minutes.
* Optional: colorant injection in standard form. Local massage of 5-10 minutes.
* After 20 minutes: transcutaneous measurement with SentiMag®
* Valuing territories (lymphoscintigraphy information?)
* Surgical identification measures:
1. st with SentiMag®
2. nd with gamma detection probe
* Ex vivo check and HRD record
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adult patients (\>18 years of age),
with diagnosis of cutaneous melanoma and
in which SLNB is indicated as a staging method, and
with cN0 result after clinical-echographic-cytohistological evaluation.
You may not be if
Previous treatment with systemic therapy.
Recent previous surgery (\<3 months) in the area susceptible of lymphatic drainage from the melanoma.
Intolerance or hypersensitivity to iron or dextran compounds.
Impossibility of use of radioisotope.
Existence of pathology related to elevation of organic iron (hemosiderosis, hemochromatosis, iron deficiency anemia of metabolic or circulatory origin).
Implantation of pacemakers or partially or totally metallic thoracic implants.
Treatment with iron chelators (deferasirox, deferoxamine, ...).
Clareo Health | Validation of Ferromagnetic Tracer in Melanoma Sentinel Node
