Dynamic of Immunocompetent Populations in Patients Treated With Extracorporeal Photopheresis in Chronic Graft Versus Host Disease

Inclusion Criteria

• •Patients aged ≥18 years who had a first allo-CSH for hematological pathology
• •Body weight ≥ 40 kg.
• •Confirmed diagnosis of inaugural cGVHD requiring systemic treatment.
• •Any source of hematopoietic stem cells is allowed.
• •All conditioning treatments are allowed.
• •Patient validated by the local investigator as eligible for treatment with ECP according to the criteria of the investigating centers
• •Patient treated according to the study plan with a ECP in 2 steps
• •Patient having signed informed consent.
• •Prophylaxis of GVH maintained during the onset of cGVHD is accepted.
• •Effective contraception for men and women of childbearing age.