Age

21–any

Sex

ALL

Healthy volunteers

Not accepted

Chronic stroke participants
Hemiparesis from first ever stroke at least 6 months prior to screening
Severe motor impairment (FMA of 7-30)
At least some voluntary shoulder and elbow muscle activation.
Acute stroke participants
Hemiparesis from first ever stroke within the past 21 days
Severe motor impairment (FMA of 3-20), or total Manual Motor Score of 1-8 combined in Shoulder Abduction and Finger Extensors

Cognitive impairment with at least moderately impaired attention, or unable to follow instructions of the MCI task
Visual impairment (such as hemianopia) preventing full view of the screen
Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest).
Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study
Inability to understand or follow commands in English due to aphasia or other reason
Diffuse or multifocal infarcts
Substantial arm pain preventing participation for 90 minutes a day
New spasticity treatment (pharmacological or Botox)

Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke