Investigation of Kinetic Oscillation Stimulation by the Chordate System S101 in the Treatment of Non Allergic Rhinitis

Exclusion Criteria

• •1. Patients with Allergic rhinitis, demonstrated by either positive skin prick test, Phadiatop or RAST during the last year.
• •2. Ongoing respiratory tract infection including nasal cavity at inclusion
• •3. Systemic steroid treatment less than 4 weeks before the inclusion in the study
• •4. Patients with a history of nasal surgery like: septoplasty, cosmetic surgery, conchal surgery or any other nasal surgery except closed reposition for nasal fracture during last year
• •5. History of frequent nose bleeds or a condition that increases the risk of excessive bleeding
• •6. Pronounced anterior septal deviation or other significant nasal pathology at endoscopic examination
• •7. Current malignancy of any kind
• •8. Known allergy to polyvinylchloride or medicinal liquid paraffin
• •9. Any disease, condition (medical or surgical) or drug or alcohol abuse which, in the opinion of the investigator, might compromise the study results, or would place the patient at increased risk.
• •10. Any implant with an electrical and/or neurostimulator device, including but not limited to cardiac pacemaker, defibrillator, vagal neurostimulator, deep brain stimulation, spinal stimulator, bone growth stimulator, or cochlear implant or any other implant in the head-, and neck region.
• •11. Previous treated with radiation on the face, head or neck regions
• •12. Female patients who are pregnant or become pregnant at any time from inclusion of the study until end of the 8 week follow-up visit
• •13. Received study drug in a clinical trial for an investigational drug within the previous 30 days, or 5 half-lives, whichever is longer