Complications of HBV,HCV,HIV.Complications of alcoholic liver disease,autoimmune liver disease,hereditary metabolic liver disease, drug-induced liver disease and other chronic liver disease.
AFP\>100ng/ml and imaging indicates malignant occupying.Or AFP still\>100ng/ml within 3 months.
Creatinine was 1.5 times higher than the upper limit of the normal value.
Combined with other malignant tumors(except those cured).
Serious diseases of heart, lung, kidney, brain, blood and other important organs with dysfunction.
severe neurological and psychiatric diseases (such as epilepsy, depression, mania, schizophrenia, etc.)
Pregnant women and breast-feeding women.
The researchers consider that it is not suitable for the patients to participate in this study.