Age

2–80

Sex

ALL

Healthy volunteers

Not accepted

Hodgkin's lymphoma, anaplastic large cell lymphoma and other CD30 positive malignancies, relapsed or refractory:
Karnofsky or Lansky score \>50;
Expected survival\>12 weeks;
Hgb \> 8.0;
FEV1, FVC and DLCO ≥50% of expected corrected for hemoglobin;
LVEF≥50%;
Creatinine\<2.5mg/dl;
Bilirubin\<2.5mg/dl;
ALT (alanine aminotransferase)/AST (aspartate aminotransferase)\<3 fold normal;
Patients must sign an informed consent.

CD30 Targeted CAR-T in Treating CD30-Expressing Lymphomas