About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Liberal Transfusion Strategy in Elderly Patients | Clinical Trials | Clareo Health

Back to clinical trial search

Active Not RecruitingPhase 3NCT03369210

Liberal Transfusion Strategy in Elderly Patients

In this prospective, multicentre, open, randomised, controlled clinical trial elderly patients (≥ 70 years) undergoing intermediate- or high-risk non-cardiac surgery will be randomised either to a lib...

Lead sponsor: Johann Wolfgang Goethe University Hospital•14 locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

Johann Wolfgang Goethe University Hospital

Collaborators

Wuerzburg University Hospital

Age

70 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Patients ≥ 70 years of age scheduled for intermediate- or high-risk non-cardiac surgery will be registered
•Registered patients will be randomised only if they indeed develop severe anaemia (if Hb level falls ≤ 9 g/dl) during surgery (=day 0) or day 1, 2, or 3 after surgery

Exclusion Criteria

•preoperative Hb level ≤ 9 g/dl
•chronic kidney disease requiring dialysis
•suspected lack of compliance with follow-up procedures
•participation in other interventional trials
•expected death within 3 months
•inability to provide informed consent with absence of a legally authorised representative/ legal guardian
•temporary inability to provide informed consent
•previous participation in our trial
•patients who are prevented from having blood and blood products according to a system of beliefs (e.g. Jehovah's Witnesses)
•preoperative autologous blood donation.

Related studies

RECRUITINGPhase 2

Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis

NCT03520647 · Severe Aplastic Anemia (SAA), Hypo-Plastic Myelodysplastic Syndrome (MDS), and more

RECRUITINGPhase 1

Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS)

NCT07223983 · Alcohol Use Disorder, Weight Loss, and more

Can Pre-operative Lean Mass Predict Weight Loss After Roux-en-Y Gastric Bypass?

NCT07565051 · Morbid Obesity Requiring Bariatric Surgery

Effect of Titrated Administration of Ciprofol on Perioperative Hypotension in Elderly Patients Undergoing Laparoscopic Abdominal Surgery: A Randomized Controlled Trial

NCT07328958 · Hypotension During Surgery

Natural History of Acquired and Inherited Bone Marrow Failure Syndromes

NCT05012111 · Severe Aplastic Anemia, Telomere Biology Disorders, and more

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: August 7, 2025Terms

Trial snapshot

StatusACTIVE_NOT_RECRUITING

PhasePHASE3

Enrollment2,470

Start dateDec 2017

Last updatedAug 7, 2025

Condition

Transfusion-dependent Anemia Surgery Anemia

Locations shown

University Hospital Augsburg

Augsburg

Berlin Charite CCM

Berlin

Charite Berlin CBF

Berlin

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 7, 2025Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions