Pathologically proven diagnosis of primary non-small cell lung cancer
3 or more measurable brain metastasis ≥3 mm outside a 5-mm margin around either hippocampus on gadolinium contrast enhanced MRI within 14 days prior to registration
KPS ≥70
Age ≥55 years
Informed consent prior to study entry
You may not be if
Patients with leptomeningeal metastases
≥3 organ sites of extracranial metastases (including lung-to-lung metastases) within 3 months
Contraindication to MRI such as implanted metal devices or foreign bodies
Prior radiation therapy (including SRS) to the brain
Clareo Health | Hippocampus-sparing WBRT and Simultaneous Integrated Boost for Multiple Brain Metastases From NSCLC